The Human Cell Atlas
Revolutionizing Our Understanding of Cellular Diversity and Dynamics
Sponsored by Tim Thomas
For the past 150 years scientists have classified cells by their structures, functions, locations, and, more recently, molecular profiles. The but the characterization of cell types and states, however, has remained surprisingly limited. This limitation has constrained our ability to understand fundamental biology and to translate this understanding to diagnose and treat of disease. Fortunately, an extraordinary opportunity is emerging because of transformative advances in experimental and computational methods.
These advances have led the scientific community to launch the Human Cell Atlas (HCA), an international collaborative consortium that aims to create comprehensive, open reference maps of all human cells—the fundamental units of life—as a basis for both understanding human health and diagnosing, monitoring, and treating disease. We expect that the HCA will have profound impact on every aspect of biology and medicine, propelling translational discoveries and applications and ultimately leading to a new era of precision medicine.
About the Speaker
Aviv Regev is a professor of biology at MIT, a Howard Hughes Medical Institute Investigator, Chair of the Faculty and Director of the Klarman Cell Observatory and Cell Circuits Program at the Broad Institute of MIT and Harvard, and she is co-chair of the organizing committee for the international Human Cell Atlas project.
Aviv is a computational and systems biologist. She studies the molecular circuitry that governs the function of mammalian cells in health and disease. She pioneered many leading experimental and computational methods for the reconstruction of circuits , including in single-cell genomics.
Aviv is a recipient of an NIH Director’s Pioneer Award, a Sloan fellowship, the Overton Prize from the International Society for Computational Biology (ISCB), the Earl and Thressa Stadtman Scholar Award from the American Society of Biochemistry and Molecular Biology, and the ISCB Innovator Award, and she is a ISCB Fellow.
She earned an M.Sc. from Tel Aviv University, studying biology, computer science, and mathematics in the Interdisciplinary Program for the Fostering of Excellence and she earned a Ph.D. in computational biology from Tel Aviv University.